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Herbal Extracts 2.5 % dervived from 1 gm each of Neem (Azadirachta Indica ), Tulsi (Ocimum Sanctum), Molsiri (Minusops Elengi), Kanol (Piper Cubeba),Patang (Caesalpina Sappa), Babool ( Acacia Arabica) , Khair (Acacia catechu), Bol (Commiphora Myrrha), Lavang ( Syzygium Aromaticum ),Dalchini ( Cannamom Zeyanicum), Elaichi (Ammomum Sublatum) , Kachur (Curcurma Zedoaria), Jayphal ( Myristica Fragrans), Akhrot ( Juglans Regia ), Ajwain ( Trachyspermum Ammi),Katfal ( Myrica Nagi), Karkatshringi ( Pistacia Integerrima),Saunf ( Foeniculum Vulgare),Marich (Piper Nigrum ), Rajjamum Ammi, Amla ( Emblica Officinalis ) , Bahera ( Terminalia Belerica) ,Haritaki ( Terminalia Chebula) , Yashti Madhu ( Gycyrrhiza Glabra ), Sod saccharin , Sod benzoate ,& Purified Water q.s.
Azadirachta indica commonly known as Neem,an ingredient in Dentosoft ®Natural Toothpaste is an evergreen tree
It possesses anti-bacterial, anti-cariogenic, anti-helminthic, anti-diabetic, anti-oxidant, astringent, anti-viral, cytotoxic, and anti-inflammatory activity. Nimbidin, Azadirachtin and nimbinin are active compounds present in Neem which are responsible for antibacterial activity. Neem bark is used as an active ingredient in a number of toothpastes and toothpowders. Neem bark has anti-bacterial properties, it is quite useful in dentistry for curing gingival problems and maintaining oral health in a natural way. Neem twigs are used as oral deodorant, toothache reliever and for cleaning of teeth. The objective of this article is to focus on the various aspects of Azadirachta indica in dentistry in order to provide a tool for future research.
Neem in (Dentosoft ®Natural )is a natural antibacterial agent. Various scientific studies have revealed its antibacterial activity
A clinical study demonstrated the effects of the leaf aqueous extract from Azadirachta indica (Neem) on adhesion, cell surface hydrophobicity and biofilm formation, which may affect the colonization by Candida albicans. The results suggest that Neem leaves have a potential anti-adhesive effect on the sample studied in vitro
Aqueous extract of Neem stick and the gallotannin-enriched extract fromMelaphis chinensis inhibited insoluble glucan synthesis and results in bacterial aggregation. It reduces the ability of streptococci to colonize tooth surfaces. Neem oil in Dentosoft ®Natural shows significant antibacterial activity and has been suggested for use in treating dental plaque.Mucoadhesive dental gel containing Azadirachta indica is found to be beneficial in reducing the plaque index and salivary bacterial count comparatively better than chlorhexidine gluconate mouthwash.
Efficacy of Neem extract in Dentosoft ®Natural against acidogenic oral bacteria in fixed orthodontic appliance patients
The primary acid-tolerant bacteria associated with dental plaque including Streptococcus mutans, Streptococcus oralis, Streptococcus sobrinus, Lactobacillus acidophilus, Streptococcus salivarius, Streptococcus mitis, Streptococcus sangui, Streptococcus intermedius, and Streptococcus anginosus that surround orthodontic appliances are a common problem in many patients undergoing orthodontic treatment. It has also been reported that presence of fixed orthodontic appliance greatly inhibits oral hygiene and creates new retentive areas for plaque and debris.
Brushing with Neem Dentosoft ®Natural toothpaste after every meal and using a mouthwash with Neem extract is recommended treatment for preventing gingivitis. In a study, Neem- Dentosoft ®Natural based mouth rinse was given to patients for assessing anti-plaque and anti-gingivitis activity. The findings conclude that Neem Dentosoft ®Natural mouth rinse is as effective as chlorhexidine in reducing periodontal indices. Neem stick is found to be effective as a toothbrush in reducing dental plaque and gingival inflammation.
Studies indicate that leaf extract of A. indica-based mouth rinse is highly efficacious and that it may be used as an alternative therapy in the treatment of periodontal disease. Gingivitis has been prevented or even reversed with regular use of Neem toothpaste and mouthwash. Indica containing Azadirachtin) as an antimicrobial agent and the effective concentration of Soluneem required to inhibit periodontopathic bacteria and to compare it with a known antiplaque agent chlorhexidine (0.2%) in vitro. Study revealed that soluneem extract did not show activity against the organisms (Bacteroids fragilis, B. distatonics, Prevotella corporis, Prevotella melagingogenica, Pepto streptococcus species)
Sodium hypochlorite has been used as root canal irrigant for decades; it causes potential weakening of the tooth structure by decreasing the hardness and structural integrity of the dentin within the root canal. To overcome this disadvantage herbal drugs are used effectively to inhibit E. faecalis that causes root canal failure in patients undergoing endodontic treatment.
Aqueous and ethanolic extract of Neem leaf inhibits S. mutans and E. faecalis which cause root canal failure in endodontic procedure. Its antioxidant and antimicrobial properties makes it a potential agent for root canal irrigation as an alternative to sodium hypochlorite. Literature suggested that the Neem (Azadirachta indica) leaf extract has significant antimicrobial effect against E. faecalis derived from infected root canal samples. The extract was found to be efficacious compared with 2% sodium hypochlorite.
Regular brushing with Neem-containing Dentosoft ®Natural toothpaste will reduce the deposition of plaque, prevents caries, and enhances the immune response for overall oral health. Frequent usage of mouthwash Dentosoft ®Natural containing Neem extract will lessen gingival problems, and also treats halitosis.
Ocimum sanctum in (Dentosoft ®Natural) is equally effective in reducing plaque and gingivitis as Chlorhexidine. The results demonstrated a significant reduction in gingival bleeding and plaque indices in both groups over a period of 15 and 30 days.
M. elengi in Dentosoft ®Natural) is known for its strengthening property for teeth.
Piper Cubeba in Dentosoft ®Natural)
Piper Cubeba in Dentosoft ®Natural) helps avoid having dental cavities and is an effective local antibiotic.
Caesalpinia Sappan in Dentosoft ®Natural)
Different kinds of cariogenic bacteria, the MIC of caesalpinia sappan lignum was between 5-10 mg x mL(-1), and the MIC of other herbs was above 20 mg x mL(-1). For the eleven kinds of predominant bacteria which normally involved in pulp periapical disease and periodontitis, the MIC of caesalpinia sappan lignum was below 0.062 5 mg x mL(-1), and the MIC of the terminalia chebula retz was between 10-20 mg x mL(-1), and the others were above 20 mg x mL(-1).(A Study)
Based on these facts Caesalpinia has good role in controlling Cariogenic Bacteria .
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Dentosoft The Toothpaste Company
Operations Commenced On 2005
Franchise Commenced On 2015
Investment INR 2lac - 5lac
|Types of Channels||Investment (If any)||Margin / Commissions||Area Requirement|
|Distributor||Rs. 20lac - 30lac||%||NIL|
Investment INR 20lac - 30lac
Delhi, Haryana, Himachal Pradesh, Jammu and Kashmir, Punjab, Uttaranchal, Uttar Pradesh
Kerala, Karnataka, Tamil Nadu, Andhra Pradesh
Assam, Meghalaya, Mizoram, Tripura, Arunachal Pradesh, Manipur, Nagaland, West Bengal, Sikkim, Odisha
Gujarat, Rajasthan, Maharashtra, Goa
Chhattisgarh, Madhya Pradesh, Bihar, Jharkhand
Andaman and Nicobar, Pondicherry, Chandigarh, Lakshadweep, Daman and Diu
How long is the franchise term for? Years